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Pediatric Hypoxic-ischemic Encephalopathy (HIE) (Intrapartum Asphyxia)

Hypoxic-ischemic encephalopathy (HIE) happens when a baby's brain does not receive enough oxygen during birth.


What is Pediatric Hypoxic-ischemic Encephalopathy (HIE) (Intrapartum Asphyxia)?

Hypoxic-ischemic encephalopathy (HIE) is a brain injury that occurs when a baby’s brain does not receive enough oxygen during birth. The condition is also sometimes called intrapartum asphyxia. It is the most common cause of severe brain injury and death in newborns.

Babies who have hypoxic-ischemic encephalopathy may experience life-long problems, such as:

Hypoxic-ischemic encephalopathy may be mild, moderate or severe. The amount and type of brain damage depends on how long the baby is without oxygen.



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