transforming pediatric health care

Gastroenterology

First evidence-based guidelines for pediatric IBS and functional abdominal pain

Learn how Children’s Health collaborated on the first-ever global guidelines for pediatric IBS and functional abdominal pain, offering gastroenterologists evidence-based recommendations to improve care for gut-brain interaction disorders.

Neonatology

Study reveals CBT reduces perceived child vulnerability after prolonged NICU stays

Standard NICU care prioritizes the infant, but parents’ perceptions of vulnerability can affect development. A new Children’s Health study shows cognitive behavioral therapy can reduce parental perceived child vulnerability after NICU discharge.

Cardiology, +1 more

Groundbreaking pediatric cardio-oncology program transforming care

Pediatric cancer treatments can save lives – but they may also carry cardiac risks that could last a lifetime.

Nephrology

Case study: siRNA therapy enables kidney-only transplant in child with rare PH1

Primary hyperoxaluria type 1 (PH1) is a rare genetic disorder that causes excess oxalate, leading to kidney failure and systemic damage. While liver transplant is the only cure, FDA-approved therapies are making kidney-only transplants a viable option.

Neurology

First-in-kind study validates safety of thalamic sampling during SEEG in Children with DRE

New study at Children’s Health confirms the safety of sampling thalamic nuclei during SEEG in pediatric patients with drug-resistant epilepsy (DRE). The findings revealed that accurate thalamic mapping can improve neuromodulation targeting.

Gastroenterology

Technically variant grafts significantly close the gap in pediatric liver transplant access

Pediatric split liver transplant surgery is rare, with only 10 U.S. centers offering it. Children’s Health began using technically variant grafts in 2024 and has since doubled the national average, expanding access and reducing waitlist mortality.

Cardiology

Pioneering 3-region perfusion technique during Norwood improves survival rate

Children’s Health Heart Center is one of the few in the nation using a groundbreaking three-region perfusion technique during the Norwood procedure. This approach maintains continuous blood flow to vital organs, reduces surgical risks and speeds recovery.

Excellence

NSQIP-Pediatric Hospital Designation

The Plano Pectus Clinic at Children’s Health earned the NSQIP-Pediatric hospital designation for exemplary outcomes in pediatric surgery.

Neonatology

Study reveals CBT reduces perceived child vulnerability after prolonged NICU stays

Standard NICU care prioritizes the infant, but parents’ perceptions of vulnerability can affect development. A new Children’s Health study shows cognitive behavioral therapy can reduce parental perceived child vulnerability after NICU discharge.

Gastroenterology

First evidence-based guidelines for pediatric IBS and functional abdominal pain

Learn how Children’s Health collaborated on the first-ever global guidelines for pediatric IBS and functional abdominal pain, offering gastroenterologists evidence-based recommendations to improve care for gut-brain interaction disorders.

Neurology

First-in-kind study validates safety of thalamic sampling during SEEG in Children with DRE

New study at Children’s Health confirms the safety of sampling thalamic nuclei during SEEG in pediatric patients with drug-resistant epilepsy (DRE). The findings revealed that accurate thalamic mapping can improve neuromodulation targeting.

Cardiology, +1 more

Groundbreaking pediatric cardio-oncology program transforming care

Pediatric cancer treatments can save lives – but they may also carry cardiac risks that could last a lifetime.

Nephrology

Case study: siRNA therapy enables kidney-only transplant in child with rare PH1

Primary hyperoxaluria type 1 (PH1) is a rare genetic disorder that causes excess oxalate, leading to kidney failure and systemic damage. While liver transplant is the only cure, FDA-approved therapies are making kidney-only transplants a viable option.

Gastroenterology

Technically variant grafts significantly close the gap in pediatric liver transplant access

Pediatric split liver transplant surgery is rare, with only 10 U.S. centers offering it. Children’s Health began using technically variant grafts in 2024 and has since doubled the national average, expanding access and reducing waitlist mortality.

Pulmonology

Bronchopulmonary dysplasia outcomes after tracheostomy: Data-driven paths to ventilator liberation

A study from Children’s Health provides insight on the timeline from tracheostomy to respiratory independence for children with bronchopulmonary dysplasia – and several keys to supporting their health and growth along the way.

Cardiology

Redefining care for congenital heart disease through pediatric-adult collaboration

By uniting pediatric and adult cardiology expertise, our Adult Congenital Heart Disease program delivers coordinated, lifelong care that improves outcomes for patients with CHD. Discover how this approach is shaping long-term survival.

Clinical Trial

A Randomized Controlled Trial of Abdominal Ultrasound (FAST) in Children with Blunt Torso Trauma

This study is a multi-center RCT to determine whether use of the FAST examination impacts care in hemodynamically stable children with blunt torso trauma.

Neurology

NCT06040255

Focal Cerebral Arteriopathy Steroid (FOCAS) Trial

Nephrology

NCT05299554

A Phase 3 Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Chronocort in the Treatment of Participants Aged 16 Years and Over with Congenital Adrenal Hyperplasia.

Neurology

Effects of Hypoglossal Nerve Stimulation on Cognition and Language in Down Syndrome and Obstructive Sleep Apnea

Hematology & Oncology

POCUS: Hemostatic Potential and Joint Health in Patients with Severe Hemophilia A on Novel Replacement Therapies

Cardiology

NCT05714085

This study aims to compare the efficacy of vericiguat versus placebo on change in n-terminal pro-brain natriuretic peptide (NTproBNP) from baseline to Week 16 of the Base Period.

Pulmonology

Comparison of Methods of Pulmonary blood flow Augmentation in neonates: Shunt versus Stent (The COMPASS Trial)

COMPASS is a prospective multicenter randomized interventional trial. Participants with ductal-dependent pulmonary blood flow will be randomized to receive either a systemic-to-pulmonary artery shunt or ductal artery stent.

Cardiology

Multicenter Trial of ECMO in Children with Severe Cardiac Failure Using the Cardiohelp System

This is a multicenter clinical trial to evaluate the safety and effectiveness of the Cardiohelp System for up to 30 days of support in children with severe cardiac failure.