transforming pediatric health care

Gastroenterology

First evidence-based guidelines for pediatric IBS and functional abdominal pain

Learn how Children’s Health collaborated on the first-ever global guidelines for pediatric IBS and functional abdominal pain, offering gastroenterologists evidence-based recommendations to improve care for gut-brain interaction disorders.

Gastroenterology

Technically variant grafts significantly close the gap in pediatric liver transplant access

Pediatric split liver transplant surgery is rare, with only 10 U.S. centers offering it. Children’s Health began using technically variant grafts in 2024 and has since doubled the national average, expanding access and reducing waitlist mortality.

Gastroenterology

A modeling breakthrough uncovers new clues to biliary atresia

The underlying cause of biliary atresia is poorly understood. A new modeling breakthrough developed with a mix of pediatric cell types reveals the altered cellular crosstalk driving the disease process – and points to a potential treatment target.

Gastroenterology

Case study: First-ever pediatric liver transplant using normothermic machine perfusion

A healthy 13‑year‑old rapidly developed acute liver failure and coma. After MARS therapy, he received the first pediatric liver transplant using a normothermic machine‑perfused donor organ at Children’s Health. He’s now getting ready to return to soccer.

Gastroenterology

Pediatric IBD: Progress Toward Precision Medicine

Gastroenterology

How to Keep Pediatric Organ Transplant Patients Safe in the COVID-19 Era

Children’s Health℠ modified practices to continue safely transplanting patients during the pandemic.

Gastroenterology

Clinical outcome and microbiome biomarkers predicting success with fiber food introduction in short bowel syndrome

This study aims to understand the pattern of tolerance of dietary fiber in SBS (short bowel syndrome) subjects vs non-SBS subjects.

Gastroenterology

NCT04336722

A Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Odevixibat (A4250) in Children with Biliary Atresia Who Have Undergone a Kasai Hepatoportoenterostomy (BOLD)

Gastroenterology

NCT05426733

Gastroenterology

NCT04862221

Gastroenterology

Gastroenterology

Gastroenterology

Gastroenterology

NCT01944696