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Pediatric polyarteritis nodosa (PAN)

Pediatric polyarteritis nodosa (poly·​ar·​ter·​i·​tis - no·​do·​sa) or PAN is a rare and often fatal condition that causes vasculitis (inflammation of the blood vessels).

Overview

What is pediatric polyarteritis nodosa (PAN)?

Polyarteritis nodosa is a life-threatening condition that causes inflammation of the blood vessels. The condition typically affects middle-aged adults and is rarely seen in children.

Inflammation in the small and medium arteries caused by pediatric polyarteritis nodosa can lead to serious damage to organs and body systems, including the heart, joints, kidneys, nervous system and digestive system.

Signs and Symptoms

What are the signs and symptoms of pediatric polyarteritis nodosa (PAN)?

Causes

What are the causes of pediatric polyarteritis nodosa (PAN)?

Polyarteritis nodosa in children is caused by an immune system malfunction. It often occurs in children who have Kawasaki disease.

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